Alpha-glycerophosphocholine alpha-GPC is a choline-containing phospholipid that can be used to augment the body and brain choline pool. In this role it serves as a precursor for both acetylcholine and phosphatidylcholine biosynthesis. Alpha-GPC and citicoline i. Following an oral dose, alpha-GPC metabolizes into choline and the phospholipid glycerophosphate.
The choline can be used for acetylcholine synthesis and neurotransmission. Because alpha-GPC is a precursor in the biosynthesis of acetylcholine, it plays a supportive role in a variety of cognitive functions, including attention, concentration, mental focus, and memory formation and recall. Alpha-GPC is found in low amounts in a variety of foods  and in breast milk.
Alpha-glycerophosphocholine Alpha-GPC is a source of choline; it is able to influence both systemic and brain concentrations of choline. Alpha-glycerophosphocholine Alpha-GPC is by weight one of the best sources of choline. This means that more might not be better under all circumstances.
Alpha-GPC is a useful choline source in liquids because of its taste and solubility. In general, the best time to take alpha-GPC is early in the day. Trabucchi, S. Govoni, F. Battaini, Farmaco Sci. Lopez, S. Battaini, S. Bergamaschi, A.
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