Information for this minor interaction is available on the professional version.
Grapefruit juice may increase the blood levels of certain medications such as levonorgestrel. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with levonorgestrel. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication.
Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact. Estrogens and progestogens may cause fluid retention, particularly when given in high dosages or for prolonged periods.
When is it needed?
Therapy with these agents should be administered cautiously in patients who have preexisting problems with excess fluid. Patients with preexisting hyperlipidemia may require closer monitoring during progestogen therapy, and adjustments made accordingly in their lipid-lowering regimen.
Progestogens can cause weight gain, which may be ificant as is the case with parenteral medroxyprogesterone and undesirable in obese patients attempting to lose weight. There are drug interactions with Plan B levonorgestrel. There are 13 disease interactions with Plan B levonorgestrel which include:. Always consult your healthcare provider to ensure the information displayed on this applies to your personal circumstances.
Triphasil ethinyl estradiol-levonorgestrel. Leiman G "Depo-medroxyprogesterone acetate as a contraceptive agent: its effect on weight and blood pressure. Premarin conjugated estrogens. Vivelle estradiol.
Estraderm estradiol. View all 25 references. Barnes RB, Roy S, Lobo RA "Comparison of lipid and androgen levels after conjugated estrogen or depo-medroxyprogesterone acetate treatment in postmenopausal women.
Who Task Force on Long-acting Agents for Fertility Regulation "Metabolic side-effects of injectable depot-medroxyprogesterone acetate, mg three-monthly, in undernourished lactating women. Amatayakul K, Sivasomboon B, Thanangkul O "A study of the mechanism of weight gain in medroxyprogesterone acetate users. View all 13 references.
Answers to frequently asked questions about
Drug Interaction Classification These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine.
Always consult your healthcare provider before starting or stopping any medication. Major Highly clinically ificant.
What is the morning after pill?
Avoid combinations; the risk of the interaction outweighs the benefit. Moderate Moderately clinically ificant. Usually avoid combinations; use it only under special circumstances. Minor Minimally clinically ificant. Unknown No interaction information available. Drug Status Availability Discontinued.